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Tag: Diabetes

  • BEST Employees Achieve Diabetes Remission Through Lifestyle Changes | Mumbai News

    BEST Employees Achieve Diabetes Remission Through Lifestyle Changes | Mumbai News

    Lifestyle helps 250+ BEST staff in diabetes remission

    Mumbai: For the last 20 months, BEST’s Mulund bus depot supervisor, Tanaji Jadhav, rarely missed his daily 10 km walk, ate a wada pav, or drank tea with sugar. He also did not take medications for diabetes that he previously took for almost 10 years daily.
    For Jadhav, along with 278 other BEST employees, diabetes was in remission in the last two years. Thanks to personal diet counselling, monthly tele-monitoring, and three-monthly checkups, a sizeable number of the 1,580 BEST drivers and conductors who have diabetes managed to either stop or reduce their daily medicines. “Apart from 279 in remission, another 400 are on reduced dosage of medicines while another 500 have brought their daily sugar levels in control with medication,” said BEST chief medical officer Dr Anil Kumar Singhal.
    In Nov 2022, the BEST Undertaking started a workplace intervention to help staff suffering from Type 2 diabetes, the most common form of diabetes that roughly affects over 75 million Indians. The programme entailed twice-a-week lectures on leading an active lifestyle and dietary advice at the ‘Diabetes Reflection Centre’ at the Dadar workshop. “We have also started a tele helpline and a WhatsApp group to disburse useful health-related information,” said Dr Singhal.
    In a country where 70% of the patients with diabetes have poor control of their blood sugar levels, such interventions help.
    As Jadhav put it: “During the first lecture I attended, I was asked about what I eat. As a driver on a busy route, I would take 15-20 cups of tea a day and would love to eat sheera. The medical team then explained that if I cut down on these food items and adopted an active exercise regimen, my sugar levels would be in control.”
    Jadhav immediately stopped binging on carbs, cut down on tea, and took up walking. “Within a few months, my sugar levels were in the normal range without medication,” he added.
    BEST general manager Anil Diggikar said, “Our medical team has taken a good initiative in changing lifestyle, incorporating new diet and other preventive measures to ensure that diabetes is reversible for several staffers. We are witnessing positive change and it’s a great initiative by the BEST medical department. We will remain committed to the cause.”
    Dr Tushar Bandgar, head of BMC-run KEM Hospital’s endocrinology department, said diabetes remission with lifestyle changes is a possibility for Type 2 diabetes patients who have a BMI of over 25, provided they were diagnosed less than five years back and aren’t on medicines such as sulfonylureas that cause hypoglycemia (low blood sugar levels).



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  • BEST Employees Achieve Diabetes Remission Through Lifestyle Changes | Mumbai News

    BEST Employees Achieve Diabetes Remission Through Lifestyle Changes | Mumbai News

    Lifestyle helps 250+ BEST staff in diabetes remission

    Mumbai: For the last 20 months, BEST’s Mulund bus depot supervisor, Tanaji Jadhav, rarely missed his daily 10 km walk, ate a wada pav, or drank tea with sugar. He also did not take medications for diabetes that he previously took for almost 10 years daily.
    For Jadhav, along with 278 other BEST employees, diabetes was in remission in the last two years. Thanks to personal diet counselling, monthly tele-monitoring, and three-monthly checkups, a sizeable number of the 1,580 BEST drivers and conductors who have diabetes managed to either stop or reduce their daily medicines. “Apart from 279 in remission, another 400 are on reduced dosage of medicines while another 500 have brought their daily sugar levels in control with medication,” said BEST chief medical officer Dr Anil Kumar Singhal.
    In Nov 2022, the BEST Undertaking started a workplace intervention to help staff suffering from Type 2 diabetes, the most common form of diabetes that roughly affects over 75 million Indians. The programme entailed twice-a-week lectures on leading an active lifestyle and dietary advice at the ‘Diabetes Reflection Centre’ at the Dadar workshop. “We have also started a tele helpline and a WhatsApp group to disburse useful health-related information,” said Dr Singhal.
    In a country where 70% of the patients with diabetes have poor control of their blood sugar levels, such interventions help.
    As Jadhav put it: “During the first lecture I attended, I was asked about what I eat. As a driver on a busy route, I would take 15-20 cups of tea a day and would love to eat sheera. The medical team then explained that if I cut down on these food items and adopted an active exercise regimen, my sugar levels would be in control.”
    Jadhav immediately stopped binging on carbs, cut down on tea, and took up walking. “Within a few months, my sugar levels were in the normal range without medication,” he added.
    BEST general manager Anil Diggikar said, “Our medical team has taken a good initiative in changing lifestyle, incorporating new diet and other preventive measures to ensure that diabetes is reversible for several staffers. We are witnessing positive change and it’s a great initiative by the BEST medical department. We will remain committed to the cause.”
    Dr Tushar Bandgar, head of BMC-run KEM Hospital’s endocrinology department, said diabetes remission with lifestyle changes is a possibility for Type 2 diabetes patients who have a BMI of over 25, provided they were diagnosed less than five years back and aren’t on medicines such as sulfonylureas that cause hypoglycemia (low blood sugar levels).



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  • How sedentary lifestyle, hypertension, and neglecting diabetes management could lead to stroke?

    How sedentary lifestyle, hypertension, and neglecting diabetes management could lead to stroke?

    How sedentary lifestyle, hypertension, and neglecting diabetes management could lead to stroke?

    Stroke is increasingly being seen in the younger population, with individuals in their 20s and 30s presenting with acute symptoms and abnormalities detected on their MRI scans. One of the key contributing factors in these cases is the lifestyle changes that have occurred over the past few decades. Identifying these risk factors early and resorting to immediate medical attention and prevention steps thus remain crucial to potentially reverse the complications of stroke.
    Risk Factors of Stroke: Poor Lifestyle, Stress & Obesity
    With increasing urbanization, individuals have turned to a sedentary lifestyle, with the level of physical activity being significantly decreased in their 20s and 30s. This is largely because of desk-based jobs that require sitting for several hours at a stretch, with little to no physical activity. This lack of physical activity directly leads to weight gain and metabolic syndrome– which can result in impaired glucose tolerance and elevated insulin levels. Higher insulin levels can contribute to an increase in cholesterol, which in turn can lead to the formation of plaques in the blood vessels.
    Thus, it becomes crucial to maintain a reasonable level of physical activity—ideally, about 40-45 minutes of aerobic exercise 5-6 days a week. This can be something as simple as brisk walking, running, or any form of aerobic activity that suits you.
    Stress is another associated cause of stroke in the young population, which leads to reduced relaxation time and sleep. Increasing weight is also a risk factor for developing a condition called obstructive sleep apnea (OSA), where oxygen levels drop drastically during sleep. OSA is more commonly seen in patients who are overweight and obese. This drop in oxygen is an independent risk factor for stroke and heart attacks. Studies have shown that even a modest amount of weight reduction significantly reduces the risk of stroke in individuals who are overweight or obese.
    Neglecting Hypertension & Diabetes Management Can Lead to Stroke.
    The prevalence of hypertension and diabetes has also increased in the younger population – which is again associated with changes in lifestyle, including stressful work practices. They are considered cumulative diseases—meaning, the longer you have them, the more likely you are to experience complications. Hypertension and diabetes are also well-recognized risk factors for stroke and have been identified as such for several decades. Today, both diseases are being observed at much younger ages than the previous generation.
    Therefore, it is essential to monitor your blood pressure periodically and blood sugar levels to ensure they are within the acceptable range. In conclusion, the major takeaway message of this World Stroke Day would be early identification of these symptoms that can help prevent complications and also get the patient to a medical facility on time during an emergency.
    (Author: Dr. Jayachandran R, Consultant – Neurology, Manipal Hospital Millers Road.)



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  • Diabetes Awareness Month: Its Not Just Sugar! This Surprising Factor Could Up Your Risk for Type 2 Diabetes, Says Nutritionist

    Diabetes Awareness Month: Its Not Just Sugar! This Surprising Factor Could Up Your Risk for Type 2 Diabetes, Says Nutritionist

    November is marked as Diabetes Awareness Month with November 14 being World Diabetes Day. Diabetes is a chronic disease that occurs when there is too much glucose (sugar) in the blood. Over time, high blood sugar levels can damage blood vessels and nerves throughout the body. If not managed properly, people with diabetes have a higher risk of other serious health problems. A person can get diabetes due to various factors including lifestyle. It is very well known that being overweight or obese, physical inactivity, and eating unhealthy carbohydrates can increase your risk of diabetes. However, in a recent Instagram video, Nutritionist and Diabetes Educator Khushboo Jain Tibrewala explains one important risk factor often ignored – stress.

    “If you are doing everything right, but your glucose levels are still not coming down, stress could be the reason. A lot of times people are diagnosed with diabetes in their 20s and 30s. Now you are too young to be getting diabetes, right? But on probing we have learned that although they might have had a genetic risk or they might be eating unhealthy food or might have bad habits, the final tipping point, that trigger that causes type 2 diabetes in their body is generally a period of high stress. It could be like a bad work environment, loss of someone you love, it could be multiple things,” the nutritionist explains in the clip.

    Also Read:5 Things Your Mouth May Indicate About Your Health, According To An Expert

    Along with using calming techniques to manage your emotions, your food choices can also help. A healthy gut promotes a healthy mind and vice versa. The nutritionist explains that instead of eating junk food during stress, eating foods that calm your gut can be beneficial to manage your stress and reduce the risk of conditions like diabetes.

    “Eat foods that are calming to your gut. This will calm the entire system and as a result, it will also calm your mind and you will be able to cope with life more effectively,” the nutritionist explains.

    Including prebiotics and probiotics in your diet is a simple and effective way to improve your gut health. Include natural foods that promote a healthy gut microbiome.

    Prebiotic foods for your diet:

    • Wholegrains
    • Legumes
    • Garlic
    • Onions
    • Leeks
    • Shitake mushrooms
    • Asparagus
    • Oats
    • Apples

    Also Read:What Are Adaptogens? Find Out How These 3 Herbs May Help You Tackle Stress Head-On

    Probiotic foods for your diet:

    • Hard cheeses
    • Kefir
    • Natural yoghurt
    • Tempeh
    • Kimchi
    • Sauerkraut

    Further, include plenty of fruits and vegetables in your diet along with antioxidant-rich healthy beverages such as green tea and hydration through water. Stay healthy!



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  • New guideline emphasizes lifestyle-first approach to diabetes

    New guideline emphasizes lifestyle-first approach to diabetes

    October 29, 2024

    3 min read


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    Key takeaways:

    • A new American College of Lifestyle Medicine guideline centers lifestyle treatments for people with type 2 diabetes and prediabetes.
    • Key goals are sustained behavior changes, continuity of care and deprescribing.

    ORLANDO — A first-ever clinical practice guideline from the American College of Lifestyle Medicine outlines practical recommendations for lifestyle interventions as first-line therapy for people with prediabetes or type 2 diabetes.

    The multidisciplinary 228-page document, currently under peer review, highlights “just lifestyle, and not any other interventions,” according to Mahima Gulati, MD, MSc, ECNU, FACE, associate professor in the department of medical sciences at the Quinnipiac University Frank H. Netter School of Medicine and a member of the guideline writing committee. Lifestyle medicine should be the primary therapy employed for treating prediabetes and type 2 diabetes, Gulati said, as poor lifestyle habits are driving the surging prevalence of diabetes.



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    Richard Rosenfeld, MD, MPH, MBA, DipABLM, Mahima Gulati, MD, MSc, ECNU, DipABLM, FACLM, and Meagan L. Grega, MD, FACLM, DipABLM (left to right) discuss a new American College of Lifestyle Medicine guideline on lifestyle interventions for diabetes. Image: Healio.

    “According to CDC data, 90% of type 2 diabetes is preventable,” Gulati said during a presentation at the Lifestyle Medicine Conference. “If there was ever a preventable condition, it is type 2 diabetes. There are 529 million people across the globe living with type 2 diabetes today and that number is going to surpass 1 billion by 2050.”

    Input from a range of specialties

    The new guideline includes input from a wide range of specialists, including endocrinologists, cardiologists, diabetes care and education specialists, pharmacists, health and wellness coaches, psychologists and sleep and sports medicine experts, as well as consumer advocates. The guideline is intended for nonpregnant adults with type 2 diabetes, prediabetes or a history of gestational diabetes. It will include recommendations that reference the six pillars of active lifestyle intervention:

    • Nutrition — extensive evidence supports a whole food, plant-predominant eating plan;
    • Physical activity — movement combats the negative effects of sedentary behavior and builds mental health;
    • Stress management — excess stress can lead to anxiety, depression, obesity and immune dysfunction;
    • Sleep — inadequate or disordered sleep depresses mood, lowers daytime caloric burn, increases hunger and causes insulin resistance;
    • Social connectedness — positive relationships enhance mental, physical and emotional health; and
    • Avoiding risky substances — avoidance reduces risk for chronic diseases and death.

    Lifestyle interventions can be “more effective than drug therapy” for preventing prediabetes from progressing to overt type 2 diabetes, according to Richard Rosenfeld, MD, MPH, MBA, DipABLM, distinguished professor and past chairman of otolaryngology at SUNY Downstate Health Science University and director of guidelines and quality for ACLM. However, only about 20% of U.S. adults report a healthy lifestyle that incorporates at least four of the six pillars, Rosenfeld said.

    “When you look at the current diabetes guidelines — and we identified eight that were very relevant to us — there is not a lot of nuance in terms of nutrition [and] physical activity,” Rosenfeld said. “Even the American Diabetes Association Standards of Care is a bit lacking in some of the pragmatic emphasis on [these recommendations]. It is a good start, but we felt we needed to fill the void with this type of project.”

    Use a ‘SMART’ goal structure

    The first three key action statements of the guideline call for advocating for lifestyle management as first-line treatment, assessing a person’s baseline lifestyle habits with regard to the six pillars of lifestyle medicine, and establishing priorities for lifestyle change that also incorporate the six pillars. Rosenfeld said health care professionals should use a SMART goal structure — which stands for Specific, Measurable, Action-oriented, Realistic, Time-sensitive goals — to support positive lifestyle change.

    “For a clinical practice guideline, this is very innovative and unusual, to have this be your first three key action statements,” Meagan L. Grega, MD, FACLM, DipABLM, co-founder and chief medical officer of the nonprofit Kellyn Foundation and ACLM conference chair, said during the presentation. “This is the foundation. If you do not know where you are starting from, how can you see where you are trying to go?”

    The guideline recommends clinicians use the SMART goal structure to prescribe aerobic and muscle strength physical activity, with a detailed evidence profile, “because they align with the guidelines for Americans,” Rosenfeld said. There is also a separate key action statement that recommends prescribing physical activity specifically to reduce sedentary time.

    ‘Find a need and fill it’

    Other recommendations include identifying sleep disorders and referring as needed for management and treatment; prescribing a nutrition plan for disease prevention and treatment that incorporates unprocessed or minimally processed foods; counseling patients about cultivating positive social connections; and identifying when a person may benefit from psychological interventions, using validated screening tools.

    The final three key action statements, which Gulati said are the most important, focus on creating sustained behavior changes using coaching and motivational interviewing, ensuring continuity of care that prescribes lifestyle interventions and specifies the frequency of visits and adjusting therapy as needed, with a goal of deprescribing medications.

    “The bottom line is: Find a need and fill it, and I think we are with this guideline,” Rosenfeld said. “This is different. This has been exciting and I have never seen a group as passionate and involved as this guideline development group. This [guideline] has the potential to have real impact on the field.”

    Publication of the guideline is expected in 2025 and will also include an executive summary and a plain-language version for consumers, Rosenfeld said.

    Healio is an official media partner of the Lifestyle Medicine Conference.

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  • Not Just Sugar: 5 Other Factors That May Be Hindering Diabetes Control

    Not Just Sugar: 5 Other Factors That May Be Hindering Diabetes Control

    Living with diabetes can be quite challenging. You may worry about taking your medicines on time, monitoring your blood sugar levels, and ensuring you’re eating the right kinds of foods. Some foods may not be suitable for you, as they can cause a sudden spike in your blood sugar levels. These include high-carb foods and drinks, processed meats, fried foods, and the most deadly of them all – sugar. While eliminating these foods from your diet is helpful, some people still struggle to manage diabetes. So, where are you going wrong? Are you missing something? Well, it’s not just the type of food you eat, but also how you eat it, along with other lifestyle factors. If you’re unable to manage diabetes, here is where you may be going wrong, as shared by nutritionist Shweta J Panchal.
    Also Read: 5 Lunchtime Mistakes Diabetics Should Avoid For Better Diabetes Management

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    Photo Credit: iStock

    5 Factors Other Than Sugar That Make Diabetes Difficult To Control:

    1. You have replaced sugar with jaggery or honey

    Sugar is a big no-no in a diabetes diet. It’s something that you should consume only in moderation, and even then, only occasionally. But replacing sugar with jaggery or honey won’t help. Let’s not forget that jaggery and honey also contain sugar, and consuming them in excess can make it difficult to manage diabetes. According to Shweta, one should practice portion control while having both of them.

    2. You are eating a lot of simple carbohydrates

    You should also avoid consuming a lot of simple carbohydrates. This is because simple carbs are digested quickly, and can cause a rapid spike in blood sugar levels. The nutritionist suggests enriching your diet with a balance of simple and complex carbohydrates. Complex carbs take longer to digest and will help keep your blood sugar in check. So, ensure to include oats, quinoa, or brown rice in your diet.

    3. Your meals do not have enough protein

    The amount of protein you consume also plays a huge role in managing diabetes. If you eat only roti and sabzi in your meals, then it’s time to change that. Protein breaks down into glucose slowly, thus ensuring your blood sugar levels don’t fluctuate. Shweta says, “It is important to have protein in all your meals throughout the day.”

    4. You do not start your meal with fibre

    According to the nutritionist, you should always start your meal with a source of fibre. Opt for a delicious salad or a hearty soup. This works in your favour, as fibre helps in blood sugar control. When you eat something after consuming a fibre-rich food, your sugar will be in control. On the other hand, skipping fibre can cause a rapid spike and fall in your blood sugar levels.

    5. You are not physically active

    Another reason you may be unable to manage diabetes is because you’re physically inactive. You may be following all the dietary guidelines, but you’re not physically active. This can make it difficult for your body to manage blood sugar levels and could be why your sugar is high. Shweta states, “Make sure to incorporate some sort of physical activity into your daily routine, as this will help improve insulin sensitivity.”
    Also Read: Worried About Early-Onset Diabetes? Try These 3 Simple Diet Strategies

    Watch the complete video below:

    Now that you know sugar is not the only culprit behind diabetes, we hope you’ll be able to manage it more effectively.



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  • Paratha, Samosa And Sugary Foods Raise Type 2 Diabetes Risk In Indians, Says ICMR Study

    Paratha, Samosa And Sugary Foods Raise Type 2 Diabetes Risk In Indians, Says ICMR Study

    Consumption of ultra-processed and fried foods can lead to chronic inflammation in the body, insulin resistance and type 2 diabetes in overweight/obese Asian-Indian adults, according to the latest study by the Madras Diabetes Research Foundation, an ICMR Centre for Advanced Research in Diabetes. The first-of-its-kind study in India has shed light on the consumption of fried and ultra-processed foods that are rich in Advanced Glycation End-products (AGEs). AGEs are a group of compounds that accumulate in the body over time and are associated with chronic diseases.
    Dr V Mohan, chairman of the Madras Diabetes Research Foundation, and Dr Mohan’s Diabetes Specialities Centre explained that the AGEs are formed in the blood. “But now we know that diet can also play a role in this. So there are diets which have high AGEs and diets which have low AGEs,” Dr Mohan said, reported PTI. Diets with high AGEs include red meat, french fries and other fried foods, bakery products, paratha, samosa and sugary foods among others.
    Also Read:Refined Oil Vs Cold Pressed Oil: Which Is Healthier For Cooking? Expert Weighs In
    The government-funded study has shown that low-AGE diets could be a potential strategy to reduce diabetes risk. Low-AGE food includes green leafy vegetables, fruits, fish, boiled items and brown rice, Dr V Mohan said. The study also noted that cooking methods like frying, roasting and grilling elevate AGE levels while boiling keeps them in check.

    Add image caption here

    Low-AGE foods may prevent diabetes risk. Photo:iStock

    The study included 38 overweight and obese Asian-Indian adults, aged 25 to 45 years, with a Body Mass Index (BMI) of 23 and above. The study observed the participants for 12 weeks and found that for those who followed a low-AGE diet, their glucose levels and inflammatory markers were lower, Dr Mookambika Ramya Bai, a research scientist at the Madras Diabetes Research Foundation and first author of the study, said. In contrast, those who ate high-AGEs foods had higher glucose levels, greater insulin resistance and more inflammatory markers in their blood.

    The rapid nutrition transition in developing countries like India has led to higher intakes of refined carbohydrates, fats and animal products. This, along with a sedentary lifestyle, increases the prevalence of obesity, diabetes and associated disorders, the study said, reported PTI. “The rise in the diabetes epidemic in India is primarily driven by obesity, physical inactivity and eating of unhealthy diets which are rich in AGEs,” Dr Mohan said.
    Also Read:The Truth About Cheat Days: Are They Really Good For You? Expert Reveals
    Prevalence of diabetes, pre-diabetes and obesity is on the rise globally and in India, there are currently 101 million individuals with diabetes, according to the study. Obesity is linked to insulin resistance, oxidative stress and inflammation, and thus, promotes the development of diseases like type 2 diabetes. The prevalence of obesity in India is 40 per cent and overweight or obesity has been linked with higher mortality, the study said. The study findings were published in the International Journal of Food Sciences and Nutrition.

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  • This Easy Karela Tikki Can Help You Lose Weight, Manage Diabetes, and More

    This Easy Karela Tikki Can Help You Lose Weight, Manage Diabetes, and More

    Do you cringe when faced with karela? We all understand that bitter gourd is beneficial for us, yet it’s not exactly our favourite. Karela is renowned for its bitterness, but with a clever approach to cooking, you’ll discover it’s not as repulsive as it seems. In fact, it might even be deemed delicious! If you’re seeking an innovative method to enjoy karela, we’ve got a simple recipe for you: karela tikki. This flavoursome tikki is a wholesome snack you shouldn’t overlook. Learn more about it below:

    Also Read: Looking For Diabetes-Friendly Snacks? This Soya Tikki Recipe Is A Must-Try

    Why Is Karela Tikki Beneficial for Your Health? Key Benefits to Recognize:

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    Karela comes with a wide range of health benefits. Photo Credit: iStock

    1. Supports Weight Loss

    This tikki is crafted using high-fibre ingredients that provide prolonged satiety. Since it’s merely pan-fried, it contains fewer calories and fats compared to deep-fried snacks. As a result, karela tikki can be a valuable inclusion in your weight loss regimen.

    2. Aids in Managing Blood Sugar Levels

    This tikki can also be embraced as part of a diabetes-friendly diet. Individuals with diabetes are often recommended to consume karela juice for its manifold advantages. However, this tikki offers an alternative way to harness those benefits. The other primary ingredients in this tikki-paneer, besan, vegetables, and spices-are all suitable for diabetics. Just be mindful of the salt content.

    3. Abundant in Nutrients

    Even if you’re not strictly dieting, indulging in this tikki is a wise consideration. Each ingredient is teeming with vitamins, minerals, and antioxidants that can elevate your overall well-being.

    Also Read:6 Easy Ways To Add Karela To Your Diabetes Diet (Recipes Inside)

    So why wait? Explore the recipe for this nourishing vegetable tikki below:

    How to Prepare Healthy Karela Tikki at Home | Effortless Recipe for Karela Snack Beneficial for Weight Loss and Diabetes

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    These veg tikkis are packed with fibre and nutrients. Photo Credit: iStock

    Begin by thoroughly washing the karela and grating its outer layer. Set the inner part aside, which can be utilized for making sabzis and other dishes. Grind the grated karela to achieve a coarse mixture. Combine it with a dash of salt and allow it to rest. Subsequently, squeeze out excess water from the mixture and transfer the karela to a spacious bowl.

    Blend the karela with minced ginger, garlic, chillies, and vegetables. Incorporate grated paneer, ajwain seeds, spice masalas, and salt. Finally, add besan and thoroughly mix all the components. Shape small portions of the prepared karela mixture into tikkis. Pan-fry them over medium heat until they acquire a golden brown hue.

    For a detailed Karela Tikkis recipe, click here.

    The next time you seek a healthful and uncomplicated snack option, opt for these karela tikkis. Share your feedback with us – let us know your thoughts!

    Also Read: Weight Loss, Heart Health, Diabetes: 5 Superfoods That Help With All Three!

    Disclaimer: This content, along with any advice offered, presents general information exclusively. It in no way substitutes a qualified medical opinion. Always consult a specialist or your personal physician for comprehensive insights. NDTV disclaims responsibility for this information.

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  • Healthy Lifestyle Mitigates Brain Aging in Diabetes

    Healthy Lifestyle Mitigates Brain Aging in Diabetes

    TOPLINE:

    Diabetes and prediabetes are associated with accelerated brain aging with brain age gaps of 2.29 and 0.50 years, respectively. This association is more pronounced in men and those with poor cardiometabolic health but may be mitigated by a healthy lifestyle.

    METHODOLOGY:

    • Diabetes is a known risk factor for cognitive impairment, dementia, and global brain atrophy but conflicting results have been reported for prediabetes, and it’s unknown whether a healthy lifestyle can counteract the negative impact of prediabetes.
    • Researchers examined the cross-sectional and longitudinal relationship between hyperglycemia and brain aging, as well as the potential mitigating effect of a healthy lifestyle in 31,229 dementia-free adults (mean age, 54.8 years; 53% women) from the UK Biobank, including 13,518 participants with prediabetes and 1149 with diabetes.
    • The glycemic status of the participants was determined by their medical history, medication use, and A1c levels.
    • The brain age gap was calculated as a difference between chronologic age and brain age estimated from MRI data from six modalities vs several hundred brain MRI phenotypes that were modeled from a subset of healthy individuals.
    • The role of sex, cardiometabolic risk factors, and a healthy lifestyle and their association with brain age was also explored, with a healthy lifestyle defined as never smoking, no or light or moderate alcohol consumption, and high physical activity.

    TAKEAWAY:

    • Prediabetes and diabetes were associated with a higher brain age gap than normoglycemia (beta-coefficient, 0.22 and 2.01; 95% CI, 0.10-0.34 and 1.70-2.32, respectively), and diabetes was more pronounced in men vs women and those with a higher vs lower burden of cardiometabolic risk factors.
    • The brain ages of those with prediabetes and diabetes were 0.50 years and 2.29 years older on average than their respective chronologic ages.
    • In an exploratory longitudinal analysis of the 2414 participants with two brain MRI scans, diabetes was linked to a 0.27-year annual increase in the brain age gap, and higher A1C, but not prediabetes, was associated with a significant increase in brain age gap.
    • A healthy lifestyle attenuated the association between diabetes and a higher brain age gap (P = .003), reducing it by 1.68 years, also with a significant interaction between glycemic status and lifestyle.

    IN PRACTICE:

    “Our findings highlight diabetes and prediabetes as ideal targets for lifestyle-based interventions to promote brain health,” the authors wrote.

    SOURCE:

    This study, led by Abigail Dove, Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden, was published online in Diabetes Care.

    LIMITATIONS:

    The generalizability of the findings was limited due to a healthy volunteer bias in the UK Biobank. A high proportion of missing data prevented the inclusion of diet in the healthy lifestyle construct. Reverse causality may be possible as an older brain may contribute to the development of prediabetes by making it more difficult to manage medical conditions and adhere to a healthy lifestyle. A1c levels were measured only at baseline, preventing the assessment of changes in glycemic control over time.

    DISCLOSURES:

    The authors reported receiving funding from the Swedish Research Council; Swedish Research Council for Health, Working Life and Welfare; Karolinska Institutet Board of Research; Riksbankens Jubileumsfond; Marianne and Marcus Wallenberg Foundation; Alzheimerfonden; and Demensfonden. They declared no relevant conflicts of interest.

    This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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  • How To Prevent Diabetes, Plus Sneaky Risk Factors for Type 2 Diabetes

    How To Prevent Diabetes, Plus Sneaky Risk Factors for Type 2 Diabetes

    Diabetes is one of the most common health conditions in the United States, affecting one in ten adults. Left unchecked, it can contribute to heart disease, chronic kidney disease, neuropathy and more complications. The good news? A few simple lifestyle choices can reduce your odds of ever developing the condition in the first place. We reached out to experts to learn how to prevent diabetes and everything you need to know about the disease.

    What is diabetes? 

    “Diabetes is a long-term condition where the body has trouble managing blood sugar levels,” says Raj Dasgupta, MD, Chief Medical Advisor for Fortune Recommends Health. “This happens when the pancreas doesn’t make enough insulin, or when the body can’t use insulin properly.” 

    Insulin is responsible for moving blood sugar into our cells, explains Dr. Dasgupta. When this process is impaired, blood sugar levels can skyrocket or drop dangerously with little notice. “Without proper management, high blood sugar can damage organs and tissues, such as the heart, kidneys, eyes and nerves,” says Dr. Dasgupta. 

    Types of diabetes 

    There are two main types of diabetes: type 1, and type 2. 

    diagram of type 1 and type 2 diabetes
    ttsz

    “In type 1 diabetes, the body is not making enough insulin,” explains Soumya Adhikari, MD, pediatric endocrinologist and associate professor at UT Southwestern Medical Center. Type 1 diabetes often develops during childhood and adolescence, and requires daily insulin medication.

    “In type 2 diabetes, the body has become resistant to the actions of insulin, which causes too high a blood glucose level,” Dr. Adhikari says. 

    Unlike type 1 diabetes, “type 2 diabetes is more common and usually develops in adults, although more children are being diagnosed nowadays,” adds Dr. Dasgupta. The rising rates of childhood can be at least partially attributed to lifestyle. “Unhealthy eating, an inactive lifestyle, and being overweight are key risk factors in developing Type 2 diabetes.”

    How to prevent diabetes

    While there’s no way to completely eliminate the risk of type 2 diabetes, there are steps you can take to reduce the risk of diabetes dramatically. Here, three smart steps:

    1. Build sustainable habits

    mature women walking outdoors to prevent diabetes
    kali9

    Both Dr. Dasgupta and Dr. Adhikari recommend healthy eating, regular exercise (brisk walking is a great option) and getting enough sleep to prevent type 2 diabetes. 

    Focus on healthy habits like maintaining a healthy weight, eating a balanced diet that includes lots of whole grains, fruits, vegetables and lean proteins and staying physically active,” advises Dr. Dasgupta. 

    “Avoid fad diets that may help you lose weight in the short-term, but can be difficult to maintain long-term,” adds Dr. Adhikari ”Instead, focus on making sustainable lifestyle changes.”

    2. Get diabetes screenings and know your risk

    Much of the discourse around diabetes focuses on obesity and weight loss. But Dr. Adhikari insists this isn’t the full story. 

    “Although being overweight or obese is a risk factor for type 2 diabetes, not everyone with the condition is overweight,” Dr. Adhikari explains. “Genetics, ethnicity and family history can also play significant roles. It’s crucial to understand that thin individuals can also develop type 2 diabetes if they have other underlying risk factors.” 

    In other words, you can be at a healthy weight, eat a healthy diet and still be at risk of developing diabetes – which is exactly why regular screenings are so important. “This highlights the need for routine screening for diabetes in individuals at risk, regardless of weight,” Dr. Adhikari says. 

    Lesser-known risk factors for diabetes include being over age 45, having a family history of type 2 diabetes, having non-alcoholic fatty liver disease or being African American, Hispanic, Latino, American Indian or Alaska Native.

    3. Focus on fiber, fiber and more fiber to prevent diabetes

    a plate filled with high fiber foods to help prevent diabetes
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    Frequent spikes in blood sugar can increase your risk of developing type 2 diabetes, which is why Dr. Dasgupta recommends a diet high in fiber. 

    Eating more high-fiber foods such as beans, nuts and whole grains, can help keep blood sugar steady,” says Dr. Dasgupta. “Some people also find that intermittent fasting or eating within a specific time frame throughout the day can improve how their body uses insulin, but this should be done carefully with a doctor’s guidance.” 

    How to prevent diabetes: The bottom line

    Diabetes is a serious disease. But with the right preventative measures, you can dramatically reduce your chances of developing it and continue to live your best, healthy life. 

    This content is not a substitute for professional medical advice or diagnosis. Always consult your physician before pursuing any treatment plan.

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