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Tag: Gout

  • Gout Gout, 100m sprint performance, sets new national record in final

    Gout Gout, 100m sprint performance, sets new national record in final

    Sprint prodigy Gout Gout has continued his metaphoric rise in Australian athletics with a stunning 100m heat run in gusty conditions at the Australian All Schools Athletics Championships in Brisbane.

    Running in the final just hours later on Friday afternoon, Gout set a personal best and new under-18 national record after winning the U18 100m final in a legal time of 10.17 (+0.9).

    Gout started behind the eight-ball before exploding over the final 50 metres with an elongated stride.

    LIVE UPDATES: Australia v India second Test

    READ MORE: Origin star drops contract bombshell on Cowboys

    READ MORE: Aussie teen’s bold call in bid to emulate Bolt

    Earlier, Gout delivered a blistering performance of 10.04 (+3.4 tail-wind) seconds to dominate his 100m heat.

    The 16-year-old’s effort is the fifth fastest all-conditions time by an Australian man in history.

    While not a legal time because of the wind, the time places him behind only Patrick Johnson, Rohan Browning, Tim Jackson and Matt Shirvington.

    Gout Gout wins his boys' U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship.

    Gout Gout wins his boy;s U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Bottom aged, Gout burst out of the blocks before hitting his full stride at the 30m mark — and never looked back.

    Gout’s recent showings have earned him comparisons to sprint legend Usain Bolt in his younger years.

    “Sure this is heavily wind-assisted but the way Gout Gout just floats across the track over the last 40 metres is incredible. Tell me it doesn’t remind you of the way Usain Bolt glided at his peak,” 9News Brisbane reporter Mark Gottlieb wrote on X.

    “Gonna be an absolute superstar this kid.”

    Gout Gout celebrates winning the boys' U18 100m final at the Australian All Schools Athletics Championship.

    Gout Gout celebrates winning the boys’ U18 100m final at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Competing at his home track, Gout will contest the 100m and 200m events at the top meet for Australian school-aged track and field athletes.

    “QSAC has a special place in my heart because of all the unforgettable memories I’ve made there. Cheering for my team and celebrating victories with friends makes it more than just a venue; it’s a part of my story for sure,” Gout said in an Athletics Australia statement ahead of the championships.

    Last month, Gout clocked an Australian Under 20 record of 20.29 seconds over 200m at the Queensland All Schools Track and Field Championships.

    In August, he announced himself on the world stage after dashing to silver in the boy’s 200m final at the World Athletics U20 Championships.

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  • Gout Gout, 100m sprint performance, sets new national record in final

    Gout Gout, 100m sprint performance, sets new national record in final

    Sprint prodigy Gout Gout has continued his metaphoric rise in Australian athletics with a stunning 100m heat run in gusty conditions at the Australian All Schools Athletics Championships in Brisbane.

    Running in the final just hours later on Friday afternoon, Gout set a personal best and new under-18 national record after winning the U18 100m final in a legal time of 10.17 (+0.9).

    Gout started behind the eight-ball before exploding over the final 50 metres with an elongated stride.

    LIVE UPDATES: Australia v India second Test

    READ MORE: Origin star drops contract bombshell on Cowboys

    READ MORE: Aussie teen’s bold call in bid to emulate Bolt

    Earlier, Gout delivered a blistering performance of 10.04 (+3.4 tail-wind) seconds to dominate his 100m heat.

    The 16-year-old’s effort is the fourth fastest all-conditions time by an Australian man in history.

    While not a legal time because of the wind, the time places him behind only Patrick Johnson, Rohan Browning and Matt Shirvington.

    Gout Gout wins his boys' U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship.

    Gout Gout wins his boy;s U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Bottom aged, Gout burst out of the blocks before hitting his full stride at the 30m mark — and never looked back.

    Gout’s recent showings have earned him comparisons to sprint legend Usain Bolt in his younger years.

    “Sure this is heavily wind-assisted but the way Gout Gout just floats across the track over the last 40 metres is incredible. Tell me it doesn’t remind you of the way Usain Bolt glided at his peak,” 9News Brisbane reporter Mark Gottlieb wrote on X.

    “Gonna be an absolute superstar this kid.”

    Gout Gout celebrates winning the boys' U18 100m final at the Australian All Schools Athletics Championship.

    Gout Gout celebrates winning the boys’ U18 100m final at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Competing at his home track, Gout will contest the 100m and 200m events at the top meet for Australian school-aged track and field athletes.

    “QSAC has a special place in my heart because of all the unforgettable memories I’ve made there. Cheering for my team and celebrating victories with friends makes it more than just a venue; it’s a part of my story for sure,” Gout said in an Athletics Australia statement ahead of the championships.

    Last month, Gout clocked an Australian Under 20 record of 20.29 seconds over 200m at the Queensland All Schools Track and Field Championships.

    In August, he announced himself on the world stage after dashing to silver in the boy’s 200m final at the World Athletics U20 Championships.

    Source link

  • Gout Gout, 100m sprint performance, sets new national record in final

    Gout Gout, 100m sprint performance, sets new national record in final

    Sprint prodigy Gout Gout has continued his metaphoric rise in Australian athletics with a stunning 100m heat run in gusty conditions at the Australian All Schools Athletics Championships in Brisbane.

    Running in the final just hours later on Friday afternoon, Gout set a personal best and new under-18 national record after winning the U18 100m final in a legal time of 10.17 (+0.9).

    Gout started behind the eight-ball before exploding over the final 50 metres with an elongated stride.

    LIVE UPDATES: Australia v India second Test

    READ MORE: Origin star drops contract bombshell on Cowboys

    READ MORE: Aussie teen’s bold call in bid to emulate Bolt

    Earlier, Gout delivered a blistering performance of 10.04 (+3.4 tail-wind) seconds to dominate his 100m heat.

    The 16-year-old’s effort is the fourth fastest all-conditions time by an Australian man in history.

    While not a legal time because of the wind, the time places him behind only Patrick Johnson, Rohan Browning and Matt Shirvington.

    Gout Gout wins his boys' U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship.

    Gout Gout wins his boy;s U18 100m heat in 10.04 seconds with a +3.4 tail-wind at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Bottom aged, Gout burst out of the blocks before hitting his full stride at the 30m mark — and never looked back.

    Gout’s recent showings have earned him comparisons to sprint legend Usain Bolt in his younger years.

    “Sure this is heavily wind-assisted but the way Gout Gout just floats across the track over the last 40 metres is incredible. Tell me it doesn’t remind you of the way Usain Bolt glided at his peak,” 9News Brisbane reporter Mark Gottlieb wrote on X.

    “Gonna be an absolute superstar this kid.”

    Gout Gout celebrates winning the boys' U18 100m final at the Australian All Schools Athletics Championship.

    Gout Gout celebrates winning the boys’ U18 100m final at the Australian All Schools Athletics Championship. Cameron Spencer via Getty Images

    Competing at his home track, Gout will contest the 100m and 200m events at the top meet for Australian school-aged track and field athletes.

    “QSAC has a special place in my heart because of all the unforgettable memories I’ve made there. Cheering for my team and celebrating victories with friends makes it more than just a venue; it’s a part of my story for sure,” Gout said in an Athletics Australia statement ahead of the championships.

    Last month, Gout clocked an Australian Under 20 record of 20.29 seconds over 200m at the Queensland All Schools Track and Field Championships.

    In August, he announced himself on the world stage after dashing to silver in the boy’s 200m final at the World Athletics U20 Championships.

    Source link

  • Ask the Doctor: ‘What is gout, and are there any lifestyle changes that can keep attacks at bay?’

    Ask the Doctor: ‘What is gout, and are there any lifestyle changes that can keep attacks at bay?’

    “My father is in his early 70s and has recently moved in with me, as we did not want him living alone due to a recent fall. He suffers from gout and seems to have very bad flare-ups. I would like to be able to help him to keep this under control but I don’t really know anything about gout. My father is a very proud man and won’t let me attend the consultant appointments with him as he says he is more than capable of going alone. What exactly is gout and are there any lifestyle modifications I can introduce at home (in conjunction with him taking his prescribed medications of course) to help keep his attacks at bay?”

    gout

    Answer from Dr Colm Kirby, Consultant Rheumatologist, Beacon Hospital

    Gout is the most common form of acute joint inflammation and is caused by the deposition of crystals within joints. The origin of the term ‘Gout’ stems from the Latin word ‘gutta’, which translates as ‘a drop’. It affects approximately 6% of men and 2% women. Older men and post-menopausal women are the most often affected due to hormonal factors.

    The crystals that result in gout attacks are formed and deposited when the blood concentration of Uric Acid increases beyond a point at which it is no longer soluble (>360 µmol/L). In other species, Uric Acid is metabolised to a more soluble compound which does not result in crystal formation, but humans lack the enzyme to perform this process. As Uric Acid levels rise, the risk of having gout attacks rises in parallel.

    Elevated Uric Acid can result from either over-production or under-excretion by our kidneys. Over-production of Uric Acid is typically caused by excess dietary purine, alcohol and fructose ingestion. Particular foods and beverages to avoid include those containing high quantities of fructose (fruit juices, sugary drinks, energy drinks), beer, red meats and seafood such as shellfish, sardines and anchovies. Under-excretion of gout is typically caused by chronic kidney diseases and certain medications such as diuretics, commonly referred to as “water tablets”.

    Fortunately, there are very effective medications available to lower Uric Acid, so-called Urate-Lowering Therapies (ULT). These medications work by inhibiting the production of Uric Acid which causes a fall in its concentration to the point where it again becomes soluble in blood, and so crystals do not form. The magic number to target is a Uric Acid concentration <360 µmol/L but in those with frequent flares a more aggressive strategy is advised, targeting a level <300.

    A big challenge in treating gout is the paradoxical risk of ULT precipitating flares of gout. As these medications exert their effect and start lowering the Uric Acid concentration, previously formed crystal lumps begin to dissolve and mobilise through the bloodstream, often precipitating in joints elsewhere, causing an acute painful attack of gout. This risk is present for approximately six months after commencing ULT. This generally causes a reluctance on the part of patients to take their ULT and so their gout is never optimally treated.

    To overcome this, anytime you commence ULT, ensure that your doctor also commences treatment that would normally be prescribed for an acute attack of gout. This medication should be used for six months alongside the ULT medication. After this six-month mark, it can be discontinued, and the ULT can then be safely used on its own.

    Have a question for the professionals you’d like answered? Get in touch with sarah.gill@image.ie with the subject headline ‘Ask The Doctor’.

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  • Otago University researchers lift the lid on gout – it’s your genes, not your diet and lifestyle

    Otago University researchers lift the lid on gout – it’s your genes, not your diet and lifestyle

    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology, hopes the findings will remove some of the stigma around gout.

    “Gout is a chronic disease with a genetic basis and is not the fault of the sufferer – the myth that gout is caused by lifestyle or diet needs to be busted.

    “This widespread myth causes shame in people with gout, making some people more likely to suffer in silence and not go and see the doctor to get a preventive drug that lowers urate in the blood and will prevent their pain.

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    “People need to understand that while specific dietary factors, such as eating red meat, can trigger gout attacks, the fundamental cause is high urate levels, crystals in the joints, and an immune system primed to ‘attack’ the crystals – genetics plays an important role in all of these processes.”

    The research identified a large number of immune genes and immune pathways that provide new targets and approaches for preventing gout attacks.

    Professor Merriman hopes these findings will lead to improved treatment for gout sufferers.

    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology.
    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology.

    “We hope that, in time, better and more accessible treatments will become available with the new targets we identified,” he says.

    One such option could be the repurposing of a drug used to treat a range of other immune-related diseases, including rheumatoid arthritis – tocilizumab targets a receptor for an immune signaller, interleukin-6, which the research identified as a new gene for gout.

    “Gout deserves more health spend resource and greater prioritisation in the health system.”

    Information about gout:

    – Gout is the most common form of arthritis in men; it affects about 3-4 times more men than women.

    – Gout attacks are caused by severe inflammation in the joints that arises from reaction to crystals of urate. These crystals form in the joints when urate levels in the body are high.

    – Diet plays a very small role in high urate levels but it is well established as a trigger of gout in people with urate crystals in their joints.

    AdvertisementAdvertise with NZME.

    – Gout can be effectively treated by drugs (such as allopurinol) which lower the urate in the blood and prevent urate crystal forming in the joints (or dissolve them if they are already there).

    – Gout is a chronic disease so treatment is lifelong.

    Source link

  • Otago University researchers lift the lid on gout – it’s your genes, not your diet and lifestyle

    Otago University researchers lift the lid on gout – it’s your genes, not your diet and lifestyle

    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology, hopes the findings will remove some of the stigma around gout.

    “Gout is a chronic disease with a genetic basis and is not the fault of the sufferer – the myth that gout is caused by lifestyle or diet needs to be busted.

    “This widespread myth causes shame in people with gout, making some people more likely to suffer in silence and not go and see the doctor to get a preventive drug that lowers urate in the blood and will prevent their pain.

    AdvertisementAdvertise with NZME.

    “People need to understand that while specific dietary factors, such as eating red meat, can trigger gout attacks, the fundamental cause is high urate levels, crystals in the joints, and an immune system primed to ‘attack’ the crystals – genetics plays an important role in all of these processes.”

    The research identified a large number of immune genes and immune pathways that provide new targets and approaches for preventing gout attacks.

    Professor Merriman hopes these findings will lead to improved treatment for gout sufferers.

    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology.
    Senior author Professor Tony Merriman, of Otago’s Department of Microbiology and Immunology.

    “We hope that, in time, better and more accessible treatments will become available with the new targets we identified,” he says.

    One such option could be the repurposing of a drug used to treat a range of other immune-related diseases, including rheumatoid arthritis – tocilizumab targets a receptor for an immune signaller, interleukin-6, which the research identified as a new gene for gout.

    “Gout deserves more health spend resource and greater prioritisation in the health system.”

    Information about gout:

    – Gout is the most common form of arthritis in men; it affects about 3-4 times more men than women.

    – Gout attacks are caused by severe inflammation in the joints that arises from reaction to crystals of urate. These crystals form in the joints when urate levels in the body are high.

    – Diet plays a very small role in high urate levels but it is well established as a trigger of gout in people with urate crystals in their joints.

    AdvertisementAdvertise with NZME.

    – Gout can be effectively treated by drugs (such as allopurinol) which lower the urate in the blood and prevent urate crystal forming in the joints (or dissolve them if they are already there).

    – Gout is a chronic disease so treatment is lifelong.

    Source link

  • Combo of Gout Genetics and Poor Lifestyle Can Up CVD Risk

    Combo of Gout Genetics and Poor Lifestyle Can Up CVD Risk

    TOPLINE:

    Genetic predisposition to gout, unfavorable lifestyle habits, and poor metabolic health are associated with an increased risk for cardiovascular disease (CVD); however, adherence to a healthy lifestyle can reduce this risk by up to 62%, even in individuals with high genetic risk.

    METHODOLOGY:

    • Researchers investigated the association between genetic predisposition to gout, combined with lifestyle habits, and the risk for CVD in two diverse prospective cohorts from different ancestral backgrounds.
    • They analyzed the data of 224,689 participants of European descent from the UK Biobank (mean age, 57.0 years; 56.1% women) and 50,364 participants of East Asian descent from the Korean Genome and Epidemiology Study (KoGES; mean age, 53.7 years; 66.0% women).
    • The genetic predisposition to gout was evaluated using a polygenic risk score (PRS) derived from a metagenome-wide association study, and the participants were categorized into low, intermediate, and high genetic risk groups based on their PRS for gout.
    • A favorable lifestyle was defined as having ≥ 3 healthy lifestyle factors, and 0-1 metabolic syndrome factor defined the ideal metabolic health status.
    • The incident CVD risk was evaluated according to genetic risk, lifestyle habits, and metabolic syndrome.

    TAKEAWAY:

    • Individuals in the high genetic risk group had a higher risk for CVD than those in the low genetic risk group in both the UK Biobank (adjusted hazard ratio [aHR], 1.10; P < .001) and KoGES (aHR, 1.31; P = .024) cohorts.
    • In the UK Biobank cohort, individuals with a high genetic risk for gout and unfavorable lifestyle choices had a 1.99 times higher risk for incident CVD than those with low genetic risk (aHR, 1.99; P < .001); similar outcomes were observed in the KoGES cohort.
    • Similarly, individuals with a high genetic risk for gout and poor metabolic health in the UK Biobank cohort had a 2.16 times higher risk for CVD than those with low genetic risk (aHR, 2.16; P < .001 for both); outcomes were no different in the KoGES cohort.
    • Improving metabolic health and adhering to a healthy lifestyle reduced the risk for CVD by 62% in individuals with high genetic risk and by 46% in those with low genetic risk (P < .001 for both).

    IN PRACTICE:

    “PRS for gout can be used for preventing not only gout but also CVD. It is possible to identify individuals with high genetic risk for gout and strongly recommend modifying lifestyle habits. Weight reduction, smoking cessation, regular exercise, and eating healthy food are effective strategies to prevent gout and CVD,” the authors wrote.

    SOURCE:

    This study was led by Ki Won Moon, MD, PhD, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea, and Sang‑Hyuk Jung, PhD, University of Pennsylvania, Philadelphia, and was published online on October 8, 2024, in RMD Open.

    LIMITATIONS: 

    The definitions of lifestyle and metabolic syndrome were different in each cohort, which may have affected the findings. Data on lifestyle behaviors and metabolic health statuses were collected at enrollment, but these variables may have changed during the follow-up period, which potentially introduced bias into the results. This study was not able to establish causality between genetic predisposition to gout and the incident risk for CVD.

    DISCLOSURES:

    This study was supported by the National Institute of General Medical Sciences and the National Research Foundation of Korea. The authors declared no competing interests.

    This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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